Beta-caryophyllene

Uses in perfumery :

Beta-Caryophyllene is used in green, spicy and woody accords for a deepening effect.

Year of discovery :

Data not available.

Natural availability :

Several plants contain a large amount of beta-Caryophyllene. Copahu Resinoid contains more than 50% beta-Caryophyllene. Clove Leaf EO contains 5 to 17% and Clove Bud EO contains 5 to 12%, among others. These plants can be used to extract natural beta-Caryophylene.

Isomerism :

In perfumery, the most used Caryophyllene is beta-Caryophyllene. When the unsaturation of this molecule is delocalized, alpha-Caryophyllene (alpha-humulene) and gamma-Caryophyllene have a smell quite similar to the beta isomer: terpenic and sweet at the same time. Valencene is a constitutional isomer of beta-Caryophyllene, although, its smell is more citrus and green.

Synthesis precursor :

Beta-Caryophyllene can be a precursor to the synthesis of other terpenes, by a Diels-Alder reaction for example.

Synthesis route :

Beta-Caryophyllene is a sesquiterpene. This means that it has three units of Isoprenes. Isoprene is a five carbon atoms diene, constituting a basis for the synthesis of terpenes by Diels-Alder reactions. Thus, Caryophylene can be synthesized from isoprene, or other easily obtainable terpenes, to shorten the synthesis.

Stability :

Terpenes tend to polymerize by oxydation. Not to be used in very alkaline bases as soap.

Other comments :

Data not available.

Allergens :

This ingredient is classified as an allergen under European Regulation 2023/1545, dated August 26, 2023.
Its presence must therefore be declared on product labels when it exceeds 0.001% in leave-on products and 0.01% in rinse-off products.

Signal word :

Danger

Hazard pictograms :

Precautionary statements :

IFRA 51^th :

This ingredient is not restricted for the 51th amendment