Farnesol (CAS N° 4602-84-0)​

Photo credits: ScenTree SAS

Farnesol

Farnesyl alcohol ; 3,7,11-trimethyl-2,6,10-dodecatrien-1-ol ; Dragosantol

Farnesol (CAS N° 4602-84-0)​

Photo credits: ScenTree SAS

Company Ingredient Name ID Comments Naturality Certifications MOQ Purity
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Farnésol - 30gr - Visit website Je me procure cet ingrédient - - -
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FARNESOL SYNTHETIQUE - Visit website Je me procure cet ingrédient - 10 grs -

Farnésol - 30gr

Certifications :

FARNESOL SYNTHETIQUE

Certifications :

Information Générales

General Presentation

  • CAS N° :

    4602-84-0
  • EINECS number :

    225-004-1
  • FEMA number :

    2478
  • FLAVIS number :

    02.029
  • JECFA number :

    1230
  • Volatility :

    Base
  • Price Range :

    €€€
Physico-chemical properties

Physico-chemical properties

  • Appearance :

    Colorless liquid
  • Density :

    0,88
  • Refractive Index @20°C :

    Data not available.
  • Optical rotation :

    Data not available.
  • Vapor pressure :

    Data not available.
  • Flash Point :

    96°C (204,8°F)
  • Molecular formula :

    C15H26O
  • Molecular Weight :

    222,37 g/mol
  • Log P :

    5,7
  • Fusion Point :

    Donnée indisponible.
  • Boiling Point :

    107°C (224,6°F)
  • Detection Threshold :

    1 ppm (0,0001%)
Utilisation

Chemistry & Uses

Uses in perfumery :

Farnesol is used for lily of the valley notes, to bring a fruity nuance. It is also used as a fixative.

Year of discovery :

Discovered in 1913

Natural availability :

Farnesol can be extracted from Ambrette Seeds Absolute, because it is found there in its (Z,E) conformation. It is also found in Petitgrain Bigarade EO and Orange Blossom Absolute, from which it can be extracted.

Isomerism :

Farnesol has four stereoisomers, due to the presence of two double bonds. Thus, these two bonds can have either a cis (Z) or trans (E) configuration. The four stereoisomer couples of Farnesol are : (Z,Z), (E,E), (Z,E) and (E,Z). In perfumery, a mixture of isomers is used most of the time, because no real olfactive difference exist between the isomers.

Synthesis precursor :

Farnesol is not used for the synthesis of another compound of olfactive interest.

Synthesis route :

Synthetic Farnesol can be obtained by isomerization of Nerolidol. This synthesis is mostly replacing the natural extraction of Farnesol, as it was formerly usual.

Stability :

Terpenes may polymerize under strong oxydation.

Other comments :

The smell of Farnesol becomes stronger when the molecule is evaporating, surely due to oxydation.
Farnesol is part of the sesquiterpene molecule category. This means that this molecule has fifteen carbon atoms, that is three isoprene units. Terpenes (monoterpenes, diterpenes, sesquiterpenes...) were discovered thanks to the Diels-Alder reaction, involving a diene and a dienophile, abling to modelize terpenes and to obtain a great variety of them.

Utilisation

IFRA

IFRA 51th :

This ingredient is restricted by the 51th amendment

  • Restriction type :

    RESTRICTION_SPECIFICATION
  • Cause of restriction :

    DERMAL SENSITIZATION
  • Amendment :

    49
Quantitative limit on the use :
Cat.1 Cat.2 Cat.3 Cat.4
Cat.5
A B C D
Cat.6
0,21 % 0,062 % 1,2 % 1,2 %
0,29 % 0,29 % 0,29 % 0,29 %
0,68 %
Cat.5
A B C D
Cat.6
0,29 % 0,29 % 0,29 % 0,29 %
0,68 %
Cat.7
A B
Cat.8 Cat.9
Cat.10
A B
Cat.11
A B
Cat.12
2,4 % 2,4 %
0,12 % 2,3 %
8,1 % 8,1 %
4,5 % 4,5 %
No Restriction
Cat.10
A B
Cat.11
A B
Cat.12
8,1 % 8,1 %
4,5 % 4,5 %
No Restriction
  • Specified ingredients: notes
    Farnesol should only be used as a fragrance ingredient if it contains a minimum of 96% of farnesol isomers as determined by GLC.
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