Tonalide®

Uses in perfumery :

Tonalide® is used in men's fragrances, in combination with other musks. Good fixator and substantivity.
Used in all types of fragrances, especially in body care. Its earthy note can stand out if this raw material is overdosed.

Year of discovery :

Discovered in 1954.

Natural availability :

Tonalide® is not available in its natural state.

Isomerism :

Galaxolide® is another musk and a constitutional isomer of Tonalide®, with a quite similar smell.

Synthesis precursor :

Tonalide® is not a precursor to the synthesis of another compound of olfactory interest.

Synthesis route :

Tonalide® is a polycyclic musk, synthesized from 1,1,2,4,4,7-hexamethyltetralin. This compound is synthesized by a reaction between alpha-para-dimethylstyrene and tetramethylethene, in an acid medium. It can also be prepared by a Friedel-Crafts reaction between para-Cymene and 3,3-dimethyl-1-butene in the presence of aluminium chloride. The last synthesis step is an acetylation with chloroacetic acid in the presence of aluminium chloride.

Stability :

Musks are very stable, as in alcoholic and in functional fragrances

Other comments :

Tonalide® has a very similar smell to Galaxolide®.
It is one of the most expensive musk.
Like some other polycyclic musks,Tonalide® is not biodegradable and causes major pollution problems. As a result, some companies have decided to ban this compound from their products.

Allergens :

This ingredient does not contain any allergen.

Signal word :

Warning

Hazard pictograms :

Precautionary statements :

IFRA 51^th :

This ingredient is not restricted for the 51th amendment