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CAS number :

28371-99-5

EINECS number :

248-995-2

FEMA number :

Data not available.

JECFA number :

Data not available.

FLAVIS number :

Data not available.

Volatility :

Base

Aspect :

Colorless liquid

Price :

€€€

Stability :

Stable in perfumes and various functionnal bases.

Density :

0,97

Molecular formula :

C₁₇H₂₆O

Molecular Weight :

246.39 g/mol

Flash Point :

>199°F (>93°C)

Log P :

Data not available.

Fusion Point :

Data not available.

Boiling Point :

Data not available.

Detection Threshold :

Data not available.

Trimofix® - Trimofix® (N°Cas : 28371-99-5)

Crédits photo: ScenTree SAS

Discovery :

Data not available.

Synthesis route :

Synthesis of Trimofix® can be done starting from its corresponding trimethylcyclododecatriene, thanks to an acetylation reaction using acetic anhydride, in the presence of boron trifluoride diethyl ether.

Synthesis precursor :

Trimofix® is not a precursor for the synthesis of another material used in perfumery.

Isomerism :

Trimofix® has three double bonds. Their conformation does not matter for this compound. It is imposed during the synthesis and no isomer is favoured. Trimofix® also is a constitutional isomer of Vertofix®, having a distinctive cedarwood smell.

Natural availability :

Trimofix® is not reported as found in nature, and can thus not be extracted from any plant.

Crédits photo: ScenTree SAS

Allergens :

This ingredient does not contain any allergen.

For more information on allergens used in perfumery, please consult our article about allergens

IFRA :

This ingredient is not restricted

Maximum usage according to the product category :
Ingredients containing
Ingredient Name	CAS N°	Estimated Concentration

Cat.1	Cat.2	Cat.3	Cat.4	Cat.5	Cat.6	Cat.7	Cat.8	Cat.9	Cat.10	Cat.11
1,34 %	1,73 %	7,1 %	21,4 %	11,2 %	34,2 %	3,6 %	2 %	5 %	2,5 %	Not restricted

Skin contact products	Non skin contact products
Leave on products	Rinse off products

List of natural ingredients containing the material presented here
Ingredient Name	Botanical Name	CAS N°	Estimated Concentration

Maximum usage according to the product category :
Ingredients containing
Ingredient Name	CAS N°	Estimated Concentration
Longifolene	475-20-7	0,4
beta-Thujone	471-15-8	0,4
alpha-Thujone	546-80-5	0,1
Thujone	76231-76-0; 1125-12-8	0,5

Cat.1	Cat.2	Cat.3	Cat.4	Cat.5A	Cat.5B	Cat.5C	Cat.5D	Cat.6
0,41 %	1,1 %	0,41 %	20 %	5,1 %	0,56 %	0,76 %	0,19 %	0,0093 %
Cat.7A	Cat.7B	Cat.8	Cat.9	Cat.10A	Cat.10B	Cat.11A	Cat.11B	Cat.12
0,67 %	0,67 %	0,19 %	2,4 %	2,4 %	6,6 %	0,19 %	0,19 %	Not restricted

List of natural ingredients containing the material presented here
Ingredient Name	Botanical Name	CAS N°	Estimated Concentration
Cananga oil	Cananga odorata (Lam.) Hook. f. & Thomson (forma macrophylla Steenis)	68606-83-7	0,4
Cedarwood oil terpenes	Juniperus mexicana Schiede	68608-32-2	18
Cedarwood oil, Atlas	Cedrus atlantica (Endl.) Manetti ex Carriere	8023-85-6	1,5
Cedarwood oil, Chinese	Cupressus funebris Endl.	1159574-01-2	19,1
Cedarwood oil, Texas	Juniperus mexicana Schiede	68990-83-0	12
Cedarwood oil, Virginian	Juniperus virginiana L.	8000-27-9	24,3
Cypress oil	Cupresssus sempervirens L.	8013-86-3	0,4
Helichrysum absolute	Helichrysum angustifolium DC.	8023-95-8	1,8
Helichrysum oil	Helichrysum angustifolium DC.	8023-95-8	0,05
Juniper berry oil	Juniperus communis L.	8002-68-4	0,4
Pine needle, dwarf, oil	Pinus pumila (Pall.) Regel	8000-26-8	0,25
Sandalwood oil, Australian	Santalum spicata (R.Br.) A.DC.	8024-35-9	0,2
Verbena absolute	Lippia citriodora (L.) Kunth	8024-12-2	0,5
Vetiver oil (all origins)	Chrysopogon zizanioides (L.) Roberty	8016-96-4	0,2
Vetiver oil (all origins)	Chrysopogon zizanioides (L.) Roberty	8016-96-4	0,2

To learn more about IFRA's standards : https://ifrafragrance.org/safe-use/understanding-the-ifra-standards
To find out the specificities of each category and the ingredients prohibited by IFRA, click article about l'IFRA

Uses in perfumery :

Trimofix® is used in woody notes and in male perfumes, to bring woody, ambery and dry power. It can be overdosed as it is sweeter than other woody-ambery materials.

Other names :

cyclisone, 1-(2,6,10-trimethyl-2,5,9-cyclododecatrien-1-yl) ethanone, fixamber, methyl-2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl ketone, trimofix 0

Other comments :

In the woody-ambery family, Trimofix® has a distinctive very dry note of sawdust, as Karanal® and Cedramber®.

Exploring the branches of scent

Annexe I :

Restriction type :

RESTRICTION QRA

Cause of restriction :

SENSITIZATION

Amendment :

43

Comments :

Quantitative usage limits :

Annexe I :

Annexe I :

Restriction type :

Cause of restriction :

DERMAL SENSITIZATION AND SYSTEMIC TOXICITY

Amendment :

49

Comments :

The natural contribution of Cedrene is determined by the sum of the natural contributions of each of its isomers.

Quantitative limit on the use :

Annexe I :