ScenTree, la nouvelle encyclopédie des ingrédients de parfum.

Exploring the branches of scent

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Crédits photo: ScenTree SAS

CAS number :

28371-99-5

EINECS number :

248-995-2

FEMA number :

Data not available.

JECFA number :

Data not available.

FLAVIS number :

Data not available.

Volatility :

Base

Appearance :

Colorless liquid

Price Range :

€€€

Stability :

Stable in perfumes and various functionnal bases.

Density :

0.97

Molecular formula :

C₁₇H₂₆O

Molecular Weight :

246.39 g/mol

Flash Point :

>199°F (>93°C)

Log P :

Data not available.

Fusion Point :

Data not available.

Boiling Point :

Data not available.

Detection Threshold :

Data not available.

Crédits photo: ScenTree SAS

Year of discovery :

Data not available.

Synthesis route :

Synthesis of Trimofix® can be done starting from its corresponding trimethylcyclododecatriene, thanks to an acetylation reaction using acetic anhydride, in the presence of boron trifluoride diethyl ether.

Synthesis precursor :

Trimofix® is not a precursor for the synthesis of another material used in perfumery.

Isomerism :

Trimofix® has three double bonds. Their conformation does not matter for this compound. It is imposed during the synthesis and no isomer is favoured. Trimofix® also is a constitutional isomer of Vertofix®, having a distinctive cedarwood smell.

Natural availability :

Trimofix® is not reported as found in nature, and can thus not be extracted from any plant.

Allergens :

This ingredient does not contain any allergen.

For more information on allergens used in perfumery, please consult our article about allergens

IFRA :

This ingredient is not restricted

Maximum usage according to the product category :
Ingredients containing
Ingredient Name	CAS N°	Estimated Concentration
Citral	5392-40-5	0,5
Geraniol	106-24-1	1
Citral	5392-40-5	2
Geraniol	106-24-1	0,5

Cat.1	Cat.2	Cat.3	Cat.4	Cat.5	Cat.6	Cat.7	Cat.8	Cat.9	Cat.10	Cat.11
1,34 %	1,73 %	7,1 %	21,4 %	11,2 %	34,2 %	3,6 %	2 %	5 %	2,5 %	Not restricted

Skin contact products	Non skin contact products
Leave on products	Rinse off products

List of natural ingredients containing the material presented here
Ingredient Name	Botanical Name	CAS N°	Estimated Concentration

Maximum usage according to the product category :
Ingredients containing
Ingredient Name	CAS N°	Estimated Concentration
Geraniol	106-24-1	1
Citral	5392-40-5	0,5
Citronellal	106-23-0	0,4
Geraniol	106-24-1	0,5
Farnesal	19317-11-4	0,2
Citral	5392-40-5	2,8
Cedrene	11028-42-5	0,3
alpha-Cedrene	469-61-4	0,2
beta-Cedrene	546-28-1	0,1
Longifolene	475-20-7	0,4
beta-Thujone	471-15-8	0,4
alpha-Thujone	546-80-5	0,1
Thujone	76231-76-0; 1125-12-8	0,5

Cat.1	Cat.2	Cat.3	Cat.4	Cat.5A	Cat.5B	Cat.5C	Cat.5D	Cat.6
0,41 %	1,1 %	0,41 %	20 %	5,1 %	0,56 %	0,76 %	0,19 %	0,0093 %
Cat.7A	Cat.7B	Cat.8	Cat.9	Cat.10A	Cat.10B	Cat.11A	Cat.11B	Cat.12
0,67 %	0,67 %	0,19 %	2,4 %	2,4 %	6,6 %	0,19 %	0,19 %	Not restricted

List of natural ingredients containing the material presented here
Ingredient Name	Botanical Name	CAS N°	Estimated Concentration
Cananga oil	Cananga odorata (Lam.) Hook. f. & Thomson (forma macrophylla Steenis)	68606-83-7	0,4
Cedarwood oil terpenes	Juniperus mexicana Schiede	68608-32-2	18
Cedarwood oil, Atlas	Cedrus atlantica (Endl.) Manetti ex Carriere	8023-85-6	1,5
Cedarwood oil, Chinese	Cupressus funebris Endl.	1159574-01-2	19,1
Cedarwood oil, Texas	Juniperus mexicana Schiede	68990-83-0	12
Cedarwood oil, Virginian	Juniperus virginiana L.	8000-27-9	24,3
Cypress oil	Cupresssus sempervirens L.	8013-86-3	0,4
Helichrysum absolute	Helichrysum angustifolium DC.	8023-95-8	1,8
Helichrysum oil	Helichrysum angustifolium DC.	8023-95-8	0,05
Juniper berry oil	Juniperus communis L.	8002-68-4	0,4
Pine needle, dwarf, oil	Pinus pumila (Pall.) Regel	8000-26-8	0,25
Sandalwood oil, Australian	Santalum spicata (R.Br.) A.DC.	8024-35-9	0,2
Verbena absolute	Lippia citriodora (L.) Kunth	8024-12-2	0,5
Vetiver oil (all origins)	Chrysopogon zizanioides (L.) Roberty	8016-96-4	0,2
Vetiver oil (all origins)	Chrysopogon zizanioides (L.) Roberty	8016-96-4	0,2

To learn more about IFRA's standards : https://ifrafragrance.org/safe-use/library
To find out the specificities of each category and the ingredients prohibited by IFRA, click article about l'IFRA
ScenTree is solely responsible for the information provided here.

Uses in perfumery :

Trimofix® is used in woody notes and in male perfumes, to bring woody, ambery and dry power. It can be overdosed as it is sweeter than other woody-ambery materials.

Other names :

cyclisone, 1-(2,6,10-trimethyl-2,5,9-cyclododecatrien-1-yl) ethanone, fixamber, methyl-2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl ketone, trimofix 0

Other comments :

In the woody-ambery family, Trimofix® has a distinctive very dry note of sawdust, as Karanal® and Cedramber®.

Exploring the branches of scent

Year of discovery :

Data not available.

Synthesis route :

Synthesis of Trimofix® can be done starting from its corresponding trimethylcyclododecatriene, thanks to an acetylation reaction using acetic anhydride, in the presence of boron trifluoride diethyl ether.

Synthesis precursor :

Trimofix® is not a precursor for the synthesis of another material used in perfumery.

Isomerism :

Trimofix® has three double bonds. Their conformation does not matter for this compound. It is imposed during the synthesis and no isomer is favoured. Trimofix® also is a constitutional isomer of Vertofix®, having a distinctive cedarwood smell.

Natural availability :

Trimofix® is not reported as found in nature, and can thus not be extracted from any plant.

Allergens :

This ingredient does not contain any allergen.

Annexe I :

Restriction type :

RESTRICTION QRA

Cause of restriction :

SENSITIZATION

Amendment :

43

Comments :

Quantitative usage limits :

Annexe I :

Annexe I :

Restriction type :

Cause of restriction :

DERMAL SENSITIZATION AND SYSTEMIC TOXICITY

Amendment :

49

Comments :

The natural contribution of Cedrene is determined by the sum of the natural contributions of each of its isomers.

Quantitative limit on the use :

Annexe I :